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CER1 Antibody

Product Specifications

Background

CER1 is a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity.

NCBI Gene ID

9350

Swiss Prot

O95813

Accession Number

O95813

Host

Rabbit

Reactivity

Human

Immunogen

This CER1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human CER1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

30 kDa

Fragment

Rabbit Ig

Symbol

CER1

NCBI Official Name

Cerberus

NCBI Organism

Homo sapiens

Background Reference 01

Tang, P.L., et.al., J. Bone Miner. Res. 24 (6), 1013-1021 (2009)

Background Reference 02

Swinkels, M.E., et.al., Am. J. Med. Genet.146A (11), 1430-1438 (2008)

Other Product Names

Cerberus, Cerberus-related protein, DAN domain family member 4, CER1, DAND4

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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