MADCAM1 Mouse Monoclonal Antibody [Clone ID: UMLBI158]

Product Specifications

Background

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) MADCAM1 mouse monoclonal antibody, clone UMLBI158

Synonyms

MACAM1

Gene Name

Homo sapiens mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), transcript variant 1, mRNA.

Gene ID

8174

UniProt

Q13477

Conjugation

Unconjugated

Related Pathways

Cell adhesion molecules (CAMs)

Field of Research

Cell adhesion molecules (CAMs)

Dilution

WB 1:2000, IHC 1:200

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.