CENPN Antibody
Product Specifications
Background
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128) . CENPN is an additional factor required for centromere assembly.
NCBI Gene ID
55839
Swiss Prot
Q96H22
Accession Number
Q96H22
Host
Rabbit
Reactivity
Human
Immunogen
This CENPN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-339 amino acids from the C-terminal region of human CENPN.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
40 kDa
Fragment
Rabbit Ig
Symbol
CENPN
NCBI Official Name
Centromere protein N
NCBI Organism
Homo sapiens
Background Reference 01
Carroll, C.W., et al. Nat. Cell Biol. 11 (7) :896-902 (2009)
Background Reference 02
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Background Reference 03
Izuta, H., et al. Genes Cells 11 (6) :673-684 (2006)
Other Product Names
Centromere protein N, CENP-N, Interphase centromere complex protein 32, CENPN, C16orf60, ICEN32
Tested Applications
WB, Flow
Protein ID
308153423
Physical Properties
Liquid
Curated Selection
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