Talarozole (R115866)
Product Specifications
CAS Number
201410-53-9
Synonyms
R115866
SKU
C18310-5mg
Smiles
CCC (CC) C (C1=CC=C (NC2=NC3=CC=CC=C3S2) C=C1) N4N=CN=C4
Molecular Formula
C21H23N5S
Additionnal Information
Talarozole (R115866) is a potent, orally active inhibitor of cytochrome P450 (CYP26) -mediated metabolism of All-trans-retinoic acid (RA) . It inhibits the conversion of RA by CYP26, with an IC50 of 0.004 μM, and enhances endogenous RA levels and All-trans-retinoic acid receptor (RAR) activation, showing potential as a targeted agent for dermatological therapy.
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