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MGST1 Antibody

Product Specifications

Background

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds.This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress.

NCBI Gene ID

4257

Swiss Prot

P10620

Accession Number

P10620

Host

Rabbit

Reactivity

Human

Immunogen

This MGST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-71 amino acids from the Central region of human MGST1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Cell Cycle, Obesity

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-481

Calculated Molecular Weight

18 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:4000

Symbol

MGST1

NCBI Official Name

Microsomal glutathione S-transferase 1

NCBI Organism

Homo sapiens

Background Reference 01

Zhang, H., IntColorectal Dis 22 (10), 1185-1194 (2007)

Background Reference 02

Prall, W.C., Mech. Ageing Dev. 128 (9), 503-510 (2007)

Background Reference 03

Haines, J.L., Invest. Ophthalmol. Vis. Sci. 47 (1), 329-335 (2006)

Other Product Names

Microsomal glutathione S-transferase 1, Microsomal GST-1, Microsomal GST-I, MGST1, GST12, MGST

Tested Applications

WB

Protein ID

121740

Physical Properties

Liquid

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