IIIM-8
IIIM-8 is a melanogenesis inhibitor. IIIM-8 inhibits pigment production both in vitro and in vivo without incurring any cytotoxicity in Human Adult Epidermal Melanocytes (HAEM) . IIIM-8 can be used for hyperpigmentation disorders research[1].
Product Specifications
CAS Number
1128053-62-2
UNSPSC
12352005
Target
Melanocortin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/iiim-8.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C(C)=O)C(O)=C(C2=CCN(C)CC2)C(O)=C1
Molecular Formula
C14H17NO4
Molecular Weight
263.29
References & Citations
[1]Naikoo SH, et al. Inhibition of melanogenesis by 3- (1'-methyltetrahydropyridinyl) -2,4-6-trihydroxy acetophenone via suppressing the activity of cAMP response element-binding protein (CREB) and nuclear exclusion of CREB-regulated transcription coactivator 1 (CRTC1) . Eur J Pharmacol. 2023 Aug 5;952:175734.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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