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GDF3 Antibody

Product Specifications

Background

GDF3 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. The function of this protein is unknown, but expression studies suggest it may be involved in regulation of the adult lymphatic and erythroid systems and embryonic development.

NCBI Gene ID

9573

Swiss Prot

Q9NR23

Accession Number

Q9NR23

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GDF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-52 amino acids from the N-terminal region of human GDF3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Symbol

GDF3

NCBI Official Name

Growth/differentiation factor 3

NCBI Organism

Homo sapiens

Background Reference 01

Clark, H.F., et al., Genome Res. 13 (10) :2265-2270 (2003) .

Background Reference 02

Ducy, P., et al., Kidney Int. 57 (6) :2207-2214 (2000) .

Background Reference 03

Caricasole, A.A., et al., Oncogene 16 (1) :95-103 (1998) .

Other Product Names

Growth/differentiation factor 3, GDF-3, GDF3

Tested Applications

WB, IHC-P

Protein ID

46397885

Physical Properties

Liquid

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