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KRT72 Antibody

Product Specifications

Background

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

140807

Swiss Prot

Q14CN4

Accession Number

Q14CN4

Host

Rabbit

Reactivity

Human

Immunogen

This KRT72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-342 amino acids from the Central region of human KRT72.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-728

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KRT72

NCBI Official Name

Keratin, type II cytoskeletal 72

NCBI Organism

Homo sapiens

Background Reference 01

Bertheau, P., et al. PLoS Med. (3), E90 (2007) :

Background Reference 02

Schweizer, J., et al. J. Cell Biol. 174 (2) :169-174 (2006)

Background Reference 03

Langbein, L., et al. J. Invest. Dermatol. 120 (4) :512-522 (2003)

Background Reference 04

Porter, R.M., et al. Br. J. Dermatol. 145 (4) :558-568 (2001)

Other Product Names

Keratin, type II cytoskeletal 72, Cytokeratin-72, CK-72, Keratin-72, K72, Type II inner root sheath-specific keratin-K6irs2, Type-II keratin Kb35, KRT72, K6IRS2, KB35, KRT6, KRT6IRS2

Tested Applications

WB

Protein ID

166218813

Physical Properties

Liquid

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