ENAH Antibody
Product Specifications
Background
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation. Required for the actin-based mobility of Listeria monocytogenes (By similarity) .
NCBI Gene ID
55740
Swiss Prot
Q8N8S7
Accession Number
Q8N8S7
Host
Rabbit
Reactivity
Human
Immunogen
This ENAH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-475 amino acids from the C-terminal region of human ENAH.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
67 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ENAH
NCBI Official Name
Protein enabled homolog
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Chattopadhyay, I., et al. Mutat. Res. 696 (2) :130-138 (2010)
Background Reference 03
Hahn, W.H., et al. Exp. Mol. Med. 41 (11) :793-801 (2009)
Background Reference 04
Gurzu, S., et al. RomMorphol Embryol 50 (2) :213-216 (2009)
Other Product Names
Protein enabled homolog, ENAH, MENA
Tested Applications
WB
Protein ID
48428086
Physical Properties
Liquid
Curated Selection
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