LDOC1L Antibody

LDOC1 (Leucine zipper protein downregulated in cancer cells) is a 146 amino acid nuclear protein that contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is downregulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kB (NF-kB) . The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. LDOC1L (Leucine zipper protein down-regulated in cancer cells-like), also known as MART6 (Mammalian retrotransposon-derived protein 6), is a 239 amino acid protein that belongs to the LDOC1 family.

This LDOC1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-186 amino acids from the C-terminal region of human LDOC1L.

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.