B4GALNT1 Antibody

Product Specifications

Background

GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G (M2) and G (D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G (M3) and G (D3) by a beta-1,4 linkage, resulting in the synthesis of G (M2) and G (D2), respectively.

NCBI Gene ID

2583

Swiss Prot

Q00973

Accession Number

Q00973

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This B4GALNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-323 amino acids from the Central region of human B4GALNT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

B4GALNT1

NCBI Official Name

Beta-1,4 N-acetylgalactosaminyltransferase 1

NCBI Organism

Homo sapiens

Background Reference 01

Chen, L.C., et al. Lung Cancer 67 (2) :216-220 (2010)

Background Reference 02

Boraska, V., et al. Clin. Biochem. 42 (9) :819-822 (2009)

Background Reference 03

Gornati, R., et al. Mol. Cell. Biochem. 298 (1-2), 59-68 (2007) :

Background Reference 04

Li, J., et al. J. Biol. Chem. 275 (52) :41476-41486 (2000)

Other Product Names

Beta-1,4 N-acetylgalactosaminyltransferase 1, (N-acetylneuraminyl) -galactosylglucosylceramide, GM2/GD2 synthase, GalNAc-T, B4GALNT1, GALGT, SIAT2

Tested Applications

Protein ID

1168736

Physical Properties

Liquid

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