NFKBIL2 Antibody

Product Specifications

Background

The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.

NCBI Gene ID

4796

Swiss Prot

Q96HA7

Accession Number

Q96HA7

Host

Rabbit

Reactivity

Human

Immunogen

This NFKBIL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 amino acids from the N-terminal region of human NFKBIL2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

151 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TONSL

NCBI Official Name

Tonsoku-like protein

NCBI Organism

Homo sapiens

Background Reference 01

Wang, Y., et al. J. Hum. Genet. 55 (8) :490-494 (2010)

Background Reference 02

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Background Reference 03

Norman, D.A., et al. Ann. Hum. Genet. 64 (PT 1), 15-23 (2000) :

Background Reference 04

Ray, P., et al. J. Biol. Chem. 270 (18) :10680-10685 (1995)

Other Product Names

Tonsoku-like protein, Inhibitor of kappa B-related protein, I-kappa-B-related protein, IkappaBR, NF-kappa-B inhibitor-like protein 2, Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2, TONSL, IKBR, NFKBIL2