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NDST3 Antibody

Product Specifications

Background

This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin.

NCBI Gene ID

9348

Swiss Prot

O95803

Accession Number

O95803

Host

Rabbit

Reactivity

Human

Immunogen

This NDST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 809-836 amino acids from the C-terminal region of human NDST3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-371

Calculated Molecular Weight

101 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NDST3

NCBI Official Name

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3

NCBI Organism

Homo sapiens

Background Reference 01

Feng, T., et al. Hum. Genet. 128 (3) :269-280 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Kalsi, G., et al. Hum. Mol. Genet. 19 (12) :2497-2506 (2010)

Background Reference 04

Krenn, E.C., et al. Biochem. Biophys. Res. Commun. 375 (3) :297-302 (2008)

Other Product Names

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3, Glucosaminyl N-deacetylase/N-sulfotransferase 3, NDST-3, hNDST-3, N-heparan sulfate sulfotransferase 3, N-HSST 3, Heparan sulfate N-deacetylase 3, 3---, Heparan sulfate N-sulfotransferase 3, 282-, NDST3, HSST3

Tested Applications

WB

Physical Properties

Liquid

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