MCAT Antibody

Product Specifications

Background

The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

27349

Swiss Prot

Q8IVS2

Accession Number

Q8IVS2

Host

Rabbit

Reactivity

Human

Immunogen

This MCAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-344 amino acids from the C-terminal region of human MCAT.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MCAT

NCBI Official Name

Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Kim, S.T., et al. Prostate 70 (16) :1729-1738 (2010)

Background Reference 02

Eeles, R.A., et al. Nat. Genet. 41 (10) :1116-1121 (2009)

Background Reference 03

Ma, J., et al. Atherosclerosis 191 (1) :63-72 (2007)

Background Reference 04

Kuhl, J.E., et al. Am. J. Physiol. Endocrinol. Metab. 290 (6), E1296-E1303 (2006) :

Other Product Names

Malonyl-CoA-acyl carrier protein transacylase, mitochondrial, MCT, Mitochondrial malonyl CoA:ACP acyltransferase, Mitochondrial malonyltransferase, [Acyl-carrier-protein] malonyltransferase, MCAT, MT