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ARX Antibody

Product Specifications

Background

This gene is a homeobox-containing gene expressed during development. The expressed protein contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This gene is thought to be involved in CNS development. Mutations in this gene cause X-linked mental retardation and epilepsy.

NCBI Gene ID

170302

Swiss Prot

Q96QS3

Accession Number

Q96QS3

Host

Rabbit

Reactivity

Human

Immunogen

This ARX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human ARX.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ARX

NCBI Official Name

Homeobox protein ARX

NCBI Organism

Homo sapiens

Background Reference 01

Shoubridge, C., et al. Hum. Mutat. 31 (8) :889-900 (2010)

Background Reference 02

Fullston, T., et al. Eur. J. Hum. Genet. 18 (2) :157-162 (2010)

Background Reference 03

Nabbout, R., et al. Epilepsy Res. 87 (1) :25-30 (2009)

Background Reference 04

Kitamura, K., et al. Hum. Mol. Genet. 18 (19) :3708-3724 (2009)

Other Product Names

Homeobox protein ARX, Aristaless-related homeobox, ARX

Tested Applications

WB

Protein ID

27923733

Physical Properties

Liquid

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