PARG Antibody
Product Specifications
Background
Poly (ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly (ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products.
NCBI Gene ID
8505
Swiss Prot
Q86W56
Accession Number
Q86W56
Host
Rabbit
Reactivity
Human
Immunogen
This PARG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 821-849 amino acids from the C-terminal region of human PARG.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
111 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PARG
NCBI Official Name
Poly (ADP-ribose) glycohydrolase
NCBI Organism
Homo sapiens
Background Reference 01
Whatcott, C.J., et al. Exp. Cell Res. 315 (20) :3477-3485 (2009)
Background Reference 02
Frizzell, K.M., et al. J. Biol. Chem. 284 (49) :33926-33938 (2009)
Background Reference 03
Erdelyi, K., et al. FASEB J. 23 (10) :3553-3563 (2009)
Background Reference 04
Ame, J.C., et al. J. Cell. Sci. 122 (PT 12), 1990-2002 (2009) :
Other Product Names
Poly (ADP-ribose) glycohydrolase, PARG
Tested Applications
WB
Protein ID
56417893
Physical Properties
Liquid
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