NCOA4 Antibody
Product Specifications
Background
This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma.
NCBI Gene ID
8031
Swiss Prot
Q13772
Accession Number
Q13772
Host
Rabbit
Reactivity
Human
Immunogen
This NCOA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-524 amino acids from the C-terminal region of human NCOA4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-335
Calculated Molecular Weight
70 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NCOA4
NCBI Official Name
Nuclear receptor coactivator 4
NCBI Organism
Homo sapiens
Background Reference 01
Sadow, P.M., et al. Endocr. Pathol. 21 (2) :73-79 (2010)
Background Reference 02
Landa, I., et al. PLoS Genet. (9), E1000637 (2009) :
Background Reference 03
Richardson, D.S., et al. Cancer Res. 69 (11) :4861-4869 (2009)
Background Reference 04
Peng, Y., et al. Am. J. Pathol. 172 (1) :225-235 (2008)
Other Product Names
Nuclear receptor coactivator 4, NCoA-4, Androgen receptor coactivator 70 kDa protein, 70 kDa AR-activator, 70 kDa androgen receptor coactivator, Androgen receptor-associated protein of 70 kDa, Ret-activating protein ELE1, NCOA4, ARA70, ELE1, RFG
Tested Applications
WB
Protein ID
8928226
Physical Properties
Liquid
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