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KLK12 Antibody

Product Specifications

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq].

NCBI Gene ID

43849

Swiss Prot

Q9UKR0

Accession Number

Q9UKR0

Host

Rabbit

Reactivity

Human

Immunogen

This KLK12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-113 amino acids from the Central region of human KLK12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KLK12

NCBI Official Name

Kallikrein-12

NCBI Organism

Homo sapiens

Background Reference 01

Klein, R.J., et al. Cancer Prev Res (Phila) 3 (5) :611-619 (2010)

Background Reference 02

Memari, N., et al. Biol. Chem. 388 (4) :427-435 (2007)

Background Reference 03

Lundwall, A., et al. Biol. Chem. 387 (6) :637-641 (2006)

Background Reference 04

Shinmura, K., et al. Hum. Mutat. 24 (3) :273-274 (2004)

Other Product Names

Kallikrein-12, 3421-, Kallikrein-like protein 5, KLK-L5, KLK12, KLKL5

Tested Applications

WB

Protein ID

9296989

Physical Properties

Liquid

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