PARP-1/Proteasome-IN-1
Product Specifications
Target
PARP|||Proteasome|||Apoptosis
Related Pathways
Proteases/Proteasome|||Apoptosis|||Ubiquitination|||DNA Damage/DNA Repair|||Chromatin/Epigenetic
Bioactivity
PARP-1/Proteasome-IN-1 (compound 42i) is a dual inhibitor of PARP-1 and the proteasome, demonstrating significant inhibitory effects on breast cancer. By downregulating the expression of BRCA1 and RAD51, it impairs homologous recombination repair and induces apoptosis (cellular death) .
Molecular Formula
C36H46BFN4O5S
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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