Mouse Pan3 Antibody

Product Specifications

Background

Functions in cytoplasmic mRNA decay. As part of the Pan nuclease complex, recruits polyadenylate-binding protein which in turn stimulates PAN2 nuclease activity (By similarity) .

NCBI Gene ID

72587

Swiss Prot

Q640Q5

Accession Number

Q640Q5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Pan3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 727-755 amino acids from the C-terminal region of mouse Pan3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

90 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Pan3

NCBI Official Name

PAB-dependent poly (A) -specific ribonuclease subunit PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}

NCBI Organism

Mus musculus

Background Reference 01

Zheng, D., et al. J. Cell Biol. 182 (1) :89-101 (2008)

Background Reference 02

Siddiqui, N., et al. J. Biol. Chem. 282 (34) :25067-25075 (2007)

Background Reference 03

Nishimura, M., et al. DNA Res. 11 (5) :315-323 (2004)

Background Reference 04

Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100 (24) :14109-14114 (2003)

Other Product Names

PAB-dependent poly (A) -specific ribonuclease subunit PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}, PAB1P-dependent poly (A) -nuclease {ECO:0000255|HAMAP-Rule:MF_03181}, PAN deadenylation complex subunit 3 {ECO:0000255|HAMAP-Rule:MF_03181}, Pan3