ARHGAP22 Antibody
Product Specifications
Background
ARHGAPs, such as ARHGAP22, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]) .
NCBI Gene ID
58504
Swiss Prot
Q7Z5H3
Accession Number
Q7Z5H3
Host
Rabbit
Reactivity
Human
Immunogen
This ARHGAP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-633 amino acids from the C-terminal region of human ARHGAP22.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
77 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ARHGAP22
NCBI Official Name
Rho GTPase-activating protein 22
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Dick, D.M., et al. Mol. Psychiatry (2010) In press :
Background Reference 03
Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)
Background Reference 04
Katoh, M., et al. Int. J. Mol. Med. 14 (2) :333-338 (2004)
Other Product Names
Rho GTPase-activating protein 22, Rho-type GTPase-activating protein 22, ARHGAP22, RHOGAP2
Tested Applications
WB
Protein ID
74750129
Physical Properties
Liquid
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