RASAL2 Antibody

Product Specifications

Background

This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs) . GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

NCBI Gene ID

9462

Swiss Prot

Q9UJF2

Accession Number

Q9UJF2

Host

Rabbit

Reactivity

Human

Immunogen

This RASAL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 675-703 amino acids from the Central region of human RASAL2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

129 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RASAL2

NCBI Official Name

Ras GTPase-activating protein nGAP

NCBI Organism

Homo sapiens

Background Reference 01

Fontaine-Bisson, B., et al. Diabetologia 53 (10) :2155-2162 (2010)

Background Reference 02

Shibui, T., et al. Biotechnol. Lett. 30 (12) :2037-2043 (2008)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Noto, S., et al. FEBS Lett. 441 (1) :127-131 (1998)

Other Product Names

Ras GTPase-activating protein nGAP, RAS protein activator-like 2, RASAL2, NGAP

Tested Applications

Protein ID

13959419

Physical Properties

Liquid

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