GRM2 Antibody (C-Term) [APR33609G]

Product Specifications

Background

Tissue Location: Detected in brain cortex (at protein level) . Widely expressed in different regions of the adult brain as well as in fetal brain.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRM2 Antibody (C-Term) [APR33609G].

Synonyms

Metabotropic glutamate receptor 2, mGluR2, GRM2, GPRC1B, MGLUR2

Gene Name

HGNC:4594

Gene ID

2912

UniProt

Q14416

Chromosomal Location

Cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite

Applications

Dilution

WB--1:2000

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

Molecular Weight

95568

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.