GRM2 Antibody (C-Term) [APR33609G]
Product Specifications
Background
Tissue Location: Detected in brain cortex (at protein level) . Widely expressed in different regions of the adult brain as well as in fetal brain.
Synonyms
Metabotropic glutamate receptor 2, mGluR2, GRM2, GPRC1B, MGLUR2
Gene Name
HGNC:4594
Gene ID
2912
UniProt
Q14416
Chromosomal Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite
Applications
WB
Dilution
WB--1:2000
Function
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Molecular Weight
95568
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRM2 Antibody (C-Term) [APR33609G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2912
Uniprot URL
https://www.uniprot.org/uniprot/Q14416
Available Sizes
Curated Selection
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