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CLTB Antibody

Product Specifications

Background

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

1212

Swiss Prot

P09497

Accession Number

P09497

Host

Rabbit

Reactivity

Human

Immunogen

This CLTB antibody is generated from rabbits immunized with a recombinant protein from human CLTB.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

25 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CLTB

NCBI Official Name

Clathrin light chain B

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 03

Martins-de-Souza, D., et al.Neural Transm 116 (3) :275-289 (2009)

Background Reference 04

Loerke, D., et al. Traffic 6 (10) :918-929 (2005)

Other Product Names

Clathrin light chain B, Lcb, CLTB

Tested Applications

WB

Physical Properties

Liquid

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