TFIIIC90 Antibody
Product Specifications
Background
Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.
NCBI Gene ID
9329
Swiss Prot
Q9UKN8
Accession Number
Q9UKN8
Host
Rabbit
Reactivity
Mouse
Immunogen
This TFIIIC90 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-244 amino acids from the N-terminal region of human TFIIIC90.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=56-142
Calculated Molecular Weight
92 kDa
Fragment
Rabbit Ig
Symbol
GTF3C4
NCBI Official Name
General transcription factor 3C polypeptide 4
NCBI Organism
Homo sapiens
Background Reference 01
Joubert, B.R., et al. Genome Med (3), 17 (2010) :
Background Reference 02
Dumay-Odelot, H., et al. J. Biol. Chem. 282 (23) :17179-17189 (2007)
Background Reference 03
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Background Reference 04
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (33) :12130-12135 (2004)
Other Product Names
General transcription factor 3C polypeptide 4, TF3C-delta, Transcription factor IIIC 90 kDa subunit, TFIIIC 90 kDa subunit, TFIIIC90, Transcription factor IIIC subunit delta, GTF3C4
Tested Applications
WB, Flow
Protein ID
212276467
Physical Properties
Liquid
Curated Selection
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