5-Hydroxy-TSU-68
Product Specifications
UNSPSC Description
5-Hydroxy-TSU-68 (compound M1) is the 5-hydroxylated indolinone derivative of TSU-68. TSU-68 is an anticancer agent that inhibits angiogenic receptor tyrosine kinases[1].
Target Antigen
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-hydroxy-tsu-68.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCC1=C(C)NC(/C=C2C(NC3=C\2C=C(O)C=C3)=O)=C1C
Molecular Weight
326.35
References & Citations
[1]Kitamura R, et, al. Identification of Human Liver Cytochrome P450 Isoforms Involved in Autoinduced Metabolism of the Antiangiogenic Agent (Z)-5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic Acid (TSU-68). Drug Metabolism and Disposition June 2008, 36 (6) 1003-1009.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N11675/5-Hydroxy-TSU-68-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N11675/
Clinical Information
No Development Reported
CAS Number
1035154-46-1
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