Cryopyrin Antibody
Product Specifications
NCBI Gene ID
114548
Swiss Prot
Q96P20
Accession Number
NP_004886.3, NP_899632.1, NP_001230062.1, NP_001120933.1, NP_001120934.1
Host
Goat
Reactivity
Human
Immunogen
The immunogen for this antibody is: C-DLYEKAKRDEPK
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
500 ug/mL
Homology
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow
Buffer
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and store at -20˚ C. Minimize freezing and thawing.
Specificity
This antibody is expected to recognise all five reported isoforms (NP_004886.3; NP_899632.1; NP_001230062.1; NP_001120933.1; NP_001120934.1) . Reported variants represent identical protein (NP_004886.3 and NP_001073289.1) .
Applications Notes
Peptide ELISA: Western Blot:Immunohistochemistry:
Symbol
NLRP3
NCBI Official Name
NLR family, pyrin domain containing 3
NCBI Organism
Homo sapiens
Background Reference 01
Kanneganti TD, Ozoren N, Body-Malapel M, Amer A, Park JH, Franchi L, Whitfield J, Barchet W, Colonna M, Vandenabeele P, Bertin J, Coyle A, Grant EP, Akira S, Nunez G. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature. 2006 Mar 9;440 (7081) :233-6. Epub 2006 Jan 11.
Other Product Names
CIAS1, cold autoinflammatory syndrome 1, AGTAVPRL, AII/AVP, C1orf7, FCAS, FCU, MWS, NALP3, PYPAF1 , AII/AVP receptor-like, Muckle-Wells syndrome, NACHT, LRR and PYD containing protein 3, PYRIN-containing APAF1-like protein 1, angiotensin/vasopressin receptor AII/AVP-like, cryopyrin
Tested Applications
ELISA, IHC
Protein ID
34878693
Physical Properties
Liquid
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