CASC4 Antibody
Product Specifications
Background
The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.
NCBI Gene ID
113201
Swiss Prot
Q6P4E1
Accession Number
Q6P4E1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CASC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human CASC4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=55-230
Calculated Molecular Weight
49 kDa
Fragment
Rabbit Ig
Symbol
CASC4
NCBI Official Name
Protein CASC4
NCBI Organism
Homo sapiens
Background Reference 01
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 02
Clark, H.F., et al. Genome Res. 13 (10) :2265-2270 (2003)
Background Reference 03
Sato, T., et al. Onkologie 26 (3) :268-271 (2003)
Background Reference 04
Scheer, M., et al. Mund Kiefer Gesichtschir 7 (3) :138-145 (2003)
Other Product Names
Protein CASC4, Cancer susceptibility candidate gene 4 protein, CASC4
Tested Applications
WB, Flow
Protein ID
74737334
Physical Properties
Liquid
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