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CASC4 Antibody

Product Specifications

Background

The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.

NCBI Gene ID

113201

Swiss Prot

Q6P4E1

Accession Number

Q6P4E1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CASC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human CASC4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

49 kDa

Fragment

Rabbit Ig

Symbol

CASC4

NCBI Official Name

Protein CASC4

NCBI Organism

Homo sapiens

Background Reference 01

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 02

Clark, H.F., et al. Genome Res. 13 (10) :2265-2270 (2003)

Background Reference 03

Sato, T., et al. Onkologie 26 (3) :268-271 (2003)

Background Reference 04

Scheer, M., et al. Mund Kiefer Gesichtschir 7 (3) :138-145 (2003)

Other Product Names

Protein CASC4, Cancer susceptibility candidate gene 4 protein, CASC4

Tested Applications

WB, Flow

Protein ID

74737334

Physical Properties

Liquid

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