Anti-ZNT8/SLC30A Antibody APC Conjugated

The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM) . Several transcript variants encoding different isoforms have been found for this gene.

E.coli-derived human ZNT8/SLC30A recombinant protein (Position: M1-C361) . Human ZNT8/SLC30A shares 80.6% and 78.1% amino acid (aa) sequence identity with mouse and rat ZNT8/SLC30A, respectively.