BAFF Antibody [C257/1638]
Product Specifications
Background
BAFF/BLyS/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors; BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3) .
NCBI Gene ID
10673
Swiss Prot
Q9Y275
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human BAFF protein was used as the immunogen for this BAFF antibody.
Clonality
Monoclonal
Clone
C257/1638
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Chemokines & Cytokines, Cancer
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-595
Fragment
IgG1
Symbol
TNFSF13B
NCBI Official Name
Tumor necrosis factor (ligand) superfamily, member 13b
NCBI Organism
Homo sapiens
Other Product Names
BAFF Antibody: DTL, BAFF, BLYS, CD257, TALL1, THANK, ZTNF4, TALL-1, TNFSF20, UNQ401/PRO738, Tumor necrosis factor ligand superfamily member 13B, B lymphocyte stimulator
Tested Applications
Flow, IF
Physical Properties
Liquid
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