TYR Antibody
Product Specifications
Background
TYR is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. It catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.
NCBI Gene ID
7299
Swiss Prot
P14679
Accession Number
NP_000363
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TYR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TYR antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-974
Calculated Molecular Weight
58 kDa
Applications Notes
TYR antibody can be used for detection of TYR by ELISA at 1:1562500. TYR antibody can be used for detection of TYR by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TYR
NCBI Official Name
Tyrosinase
NCBI Organism
Homo sapiens
Background Reference 01
Bidinost, C., (2006) Invest. Ophthalmol. Vis. Sci. 47 (4), 1486-1490.
Other Product Names
TYR, OCA1A, OCAIA, ATN, CMM8, OCA1, SHEP3
Tested Applications
ELISA, WB
Protein ID
4507753
Physical Properties
Liquid
Curated Selection
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