Obestatin (human)

Obestatin (human) is a 23-amino acid amidated peptide that regulates appetite and gastrointestinal motility via its interaction with GPR39. Obestatin (human) can be used for weight loss. Obestatin (human) cannot penetrate the cell membrane[1][2].

Product Specifications

CAS Number

[1081110-72-6]

UNSPSC

12352209

Target

Apoptosis; GPR39; PERK

Type

Peptides

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; GPCR/G Protein

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/obestatin-human.html

Purity

99.74

Solubility

DMSO : 1.96 mg/mL (ultrasonic; adjust pH to 5 with HCl)

Smiles

C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)C)=O)CCC(N)=O)=O)CO)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)=O)CCC(N)=O)=O)C(C)C)=O)=O)CO)=O)CC(C)C)=O)CCCCN)=O)[C@H](CC)C)=O)=O)[C@@H](C)C)=O)CC(O)=O)=O)(=O)[C@H]4N(C([C@@H](NC([C@@H](NC([C@H](CC5=CC=CC=C5)N)=O)CC(N)=O)=O)C)=O)CCC4

Molecular Formula

C116H176N32O33

Molecular Weight

2546.86

References & Citations

[1]Guangcai Ren, et al. Effect of TAT-obestatin on proliferation, differentiation, apoptosis and lipolysis in 3T3-L1 preadipocytes. J Pept Sci. 2013 Nov;19 (11) :684-91.|[2]Jian V Zhang, et al. Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science. 2005 Nov 11;310 (5750) :996-9.