CPSF2 Antibody
Product Specifications
Background
CPSF2 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. It belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily.
NCBI Gene ID
53981
Swiss Prot
Q9P2I0
Accession Number
NP_059133
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1301 - Human Heart Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CPSF2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=29-435
Calculated Molecular Weight
88 kDa
Applications Notes
CPSF2 antibody can be used for detection of CPSF2 by ELISA at 1:62500. CPSF2 antibody can be used for detection of CPSF2 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CPSF2
NCBI Official Name
Cleavage and polyadenylation specific factor 2, 100kDa
NCBI Organism
Homo sapiens
Background Reference 01
Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007) .
Other Product Names
CPSF2, CPSF100, KIAA1367
Tested Applications
ELISA, WB
Protein ID
34101288
Physical Properties
Liquid
Curated Selection
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