[Asn23]-beta-Amyloid (1-42), iowa mutation
[Asn23]-beta-Amyloid (1-42), iowa mutation is a biological active peptide. (Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. The Iowa mutation, where Asp 23 is replaced with Asn, is associated with severe cerebral amyloid beta-protein angiopathy (CAA) . The affected individuals share a missense mutation in APP at position 694. The mutated beta-amyloid peptide aggregates more rapidly and forms toxic fibrils.)
Product Specifications
UNSPSC
12352209
Target
Amyloid-β
Type
Peptides
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/asn23-beta-amyloid-1-42-iowa-mutation.html
Solubility
10 mM in DMSO
Smiles
Molecular Formula
C203H312N56O59S
Molecular Weight
4513.05
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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