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ISG20 Antibody

Product Specifications

Background

ISG20 belongs to the the exonuclease superfamily. It is exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. It degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. It is involved in the antiviral function of IFN against RNA viruses.

NCBI Gene ID

3669

Swiss Prot

Q96AZ6

Accession Number

NP_002192

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ISG20.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ISG20 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

20 kDa

Applications Notes

ISG20 antibody can be used for detection of ISG20 by ELISA at 1:312500. ISG20 antibody can be used for detection of ISG20 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

ISG20

NCBI Official Name

Interferon stimulated exonuclease gene 20kDa

NCBI Organism

Homo sapiens

Background Reference 01

Horio, T., FEBS Lett. 577 (1-2), 111-116 (2004) .

Other Product Names

ISG20, CD25, HEM45

Tested Applications

ELISA, WB

Protein ID

6857800

Physical Properties

Liquid

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