ISG20 Antibody
Product Specifications
Background
ISG20 belongs to the the exonuclease superfamily. It is exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. It degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. It is involved in the antiviral function of IFN against RNA viruses.
NCBI Gene ID
3669
Swiss Prot
Q96AZ6
Accession Number
NP_002192
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ISG20.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ISG20 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
20 kDa
Applications Notes
ISG20 antibody can be used for detection of ISG20 by ELISA at 1:312500. ISG20 antibody can be used for detection of ISG20 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ISG20
NCBI Official Name
Interferon stimulated exonuclease gene 20kDa
NCBI Organism
Homo sapiens
Background Reference 01
Horio, T., FEBS Lett. 577 (1-2), 111-116 (2004) .
Other Product Names
ISG20, CD25, HEM45
Tested Applications
ELISA, WB
Protein ID
6857800
Physical Properties
Liquid
Curated Selection
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