Rhodblock 6

Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits phospho-MRLC (myosin regulatory light chain) localization[1].

Product Specifications

CAS Number

[886625-06-5]

UNSPSC

12352005

Hazard Statement

H302

Target

ROCK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rhodblock-6.html

Purity

98.94

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC2=C(C=C1)NN=C2)C3CCC3

Molecular Formula

C12H13N3O

Molecular Weight

215.25

Precautions

H302

References & Citations

[1]Adam B Castoreno, et al. Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis. Nat Chem Biol. 2010 Jun;6 (6) :457-63.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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