HOXC11 Antibody

HOXC11 belongs to the homeobox family. The homeobox family is a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. HOXC11 is one of several homeobox HOXC proteins. HOXC11 binds to a promoter element of the lactase-phlorizin hydrolase. It may also play a role in early intestinal development.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HOXC11 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

HOXC11 antibody can be used for detection of HOXC11 by ELISA at 1:1562500. HOXC11 antibody can be used for detection of HOXC11 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.