GTF2A1 Antibody
Product Specifications
Background
GTF2A1 belongs to the TFIIA subunit 1 family. It is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. This protein induces a conformational change within the TBP/TATA complex that enhances its stability under both in vitro and physiological salt conditions.
NCBI Gene ID
2957
Swiss Prot
P52655
Accession Number
NP_056943
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GTF2A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GTF2A1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
41 kDa
Applications Notes
GTF2A1 antibody can be used for detection of GTF2A1 by ELISA at 1:62500. GTF2A1 antibody can be used for detection of GTF2A1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GTF2A1
NCBI Official Name
General transcription factor IIA, 1, 19/37kDa
NCBI Organism
Homo sapiens
Background Reference 01
Hieb, A.R., (2007) J. Mol. Biol. 372 (3), 619-632.
Other Product Names
GTF2A1, MGC129969, MGC129970, TF2A1, TFIIA, TFIIAL, TFIIA-42
Tested Applications
ELISA, WB
Protein ID
7706735
Physical Properties
Liquid
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