ML218
Product Specifications
CAS Number
1346233-68-8
Target
Calcium Channel
Applications
Neuronal Signaling
Molecular Formula
C19H26Cl2N2O
Additionnal Information
ML218 is a potent, selective, and orally active inhibitor of T-type Ca2+ channels (Cav3.1, Cav3.2, and Cav3.3), with IC50 of 310 nM for Cav3.2 and 270 nM for Cav3.3. It effectively suppresses burst activity in subthalamic nucleus (STN) neurons.
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