ONECUT2 Antibody
Product Specifications
Background
ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF) -6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism. This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.
NCBI Gene ID
9480
Swiss Prot
O95948
Accession Number
NP_004843
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ONECUT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
721_B Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ONECUT2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=25-383
Calculated Molecular Weight
54 kDa
Applications Notes
ONECUT2 antibody can be used for detection of ONECUT2 by ELISA at 1:1562500. ONECUT2 antibody can be used for detection of ONECUT2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ONECUT2
NCBI Official Name
One cut homeobox 2
NCBI Organism
Homo sapiens
Background Reference 01
Rauch, T., (2006) Cancer Res. 66 (16), 7939-7947.
Other Product Names
ONECUT2, MGC120377, MGC120378, OC-2, OC2
Tested Applications
ELISA, WB
Protein ID
119220564
Physical Properties
Liquid
Curated Selection
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