ERBB2IP Antibody
Product Specifications
Background
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
NCBI Gene ID
55914
Swiss Prot
Q96RT1
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1152-1371 of human ERBB2IP (NP_061165.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Chemokines & Cytokines, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 182kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ERBB2IP
Positive Control 2
HepG2
NCBI Official Name
Erbb2 interacting protein
NCBI Organism
Homo sapiens
Other Product Names
ERBB2IP, HEL-S-78, LAP2, erbin, densin-180-like protein, epididymis secretory protein Li 78, protein LAP2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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