ICAM4 Antibody

Product Specifications

Background

This gene encodes the Landsteiner-Wiener (LW) blood group antigen (s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW (A) /LW (B) blood group antigens is a single aa variation at position 100; Gln-100=LW (A) and Arg-100=LW (B) . Alternative splicing results in multiple transcript variants encoding distinct isoforms.

NCBI Gene ID

3386

Swiss Prot

Q14773

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-140 of human ICAM4 (NP_001034221.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Immunology, Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 29kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

ICAM4

Positive Control 2

Jurkat

Positive Control 3

SW480

Positive Control 4

Mouse brain

Positive Control 5

Mouse spleen

Positive Control 6

Mouse heart

NCBI Official Name

Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)

NCBI Organism

Homo sapiens

Other Product Names

ICAM4, intercellular adhesion molecule 4 (Landsteiner-Wiener blood group), CD242, LW, CD242 antigen, LW blood group protein, Landsteiner-Wiener blood group antigen a, Landsteiner-Wiener blood group glycoprotein, intercellular adhesion molecule 4, intercel