PRMT5 Antibody

Product Specifications

NCBI Gene ID

10419

Swiss Prot

O14744

Accession Number

NP_006100.2, NP_001034708.1

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: RACREKDRDPEAQ

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Homeostasis

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Mouse, Rat, Pig, Dog, Cow

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Calculated Molecular Weight

Approx 70kDa

Specificity

This antibody is expected to recognize both isoforms (NP_006100.2; NP_001034708.1) .

Applications Notes

Peptide ELISA: Western Blot:

Symbol

PRMT5

NCBI Official Name

Protein arginine methyltransferase 5

NCBI Organism

Homo sapiens

Background Reference 01

Zhao Q, Rank G, Tan YT, Li H, Moritz RL, Simpson RJ, Cerruti L, Curtis DJ, Patel DJ, Allis CD, Cunningham JM, Jane SM.PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.