MYOT Antibody
Product Specifications
Background
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
NCBI Gene ID
9499
Swiss Prot
Q9UBF9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 259-314 of human MYOT (NP_001129412.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=22-222
Calculated Molecular Weight
Observed: 55kDa
Fragment
IgG
Symbol
MYOT
Positive Control 2
HepG2
Positive Control 3
Mouse skeletal muscle
Positive Control 4
Mouse heart
Positive Control 5
Rat skeletal muscle
Positive Control 6
Rat heart
NCBI Official Name
Myotilin
NCBI Organism
Homo sapiens
Other Product Names
MYOT, myotilin, LGMD1, LGMD1A, TTID, 57 kDa cytoskeletal protein, OTTHUMP00000159430, OTTHUMP00000223460, OTTHUMP00000223461, myofibrillar titin-like Ig domains protein, titin immunoglobulin domain protein (myotilin)
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
