What is the catalog number for Punicalin?

The catalog number for Punicalin is HY-N0639.

What sizes are available for Punicalin?

Punicalin is available in the following size(s): 1 mg, 5 mg, 10 mg.

How many pack sizes does Punicalin come in?

Punicalin is available in 3 different pack sizes.

Is Punicalin in stock?

Punicalin is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Punicalin?

Punicalin is manufactured by QuantiMol.

What is the estimated delivery time for Punicalin?

Estimated delivery time for Punicalin is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Punicalin?

The safety data sheet for Punicalin is available here: http://file.medchemexpress.com/batch_PDF/HY-N0639/Punicalin-SDS-MedChemExpress.pdf.

Punicalin

Punicalin is a species that can be isolated from the leaves of Punica granatum. Punicalin is an active molecule against hepatitis b virus (HBV) . Punicalin can induce pyroptosis. Punicalin is a Carbonic anhydrase inhibitor. Punicalin blocks the binding of S-glycoprotein and ACE2 receptors. Pnuicalin has anti-inflammatory, antioxidant and antiviral activity[1][2][3][4][5][6][7].

Product Specifications

CAS Number

65995-64-4

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Carbonic Anhydrase; HBV; Pyroptosis

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/punicalin.html

Purity

99.88

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=C1C(C(C(C(O)=C(O)C(O)=C2)=C2C(OC(C3O)C(O)C(O)C=O)=O)=C(O)C(O)=C4OC5=O)=C4C6=C5C(C7=C(C(OC3)=O)C=C(O)C(O)=C7O)=C(O)C(O)=C6O1

Molecular Formula

C34H22O22

Molecular Weight

782.53

Precautions

H302, H315, H319, H335

References & Citations

[1]Lin CC, et al. Effects of punicalagin and punicalin on carrageenan-induced inflammation in rats. Am J Chin Med. 1999;27 (3-4) :371-6.|[2]Liu C, et al. Identification of hydrolyzable tannins (punicalagin, punicalin and geraniin) as novel inhibitors of hepatitis B virus covalently closed circular DNA. Antiviral Res. 2016 Oct;134:97-107.|[3]Shen R, et al. Punicalin Ameliorates Cell Pyroptosis Induced by LPS/ATP Through Suppression of ROS/NLRP3 Pathway. J Inflamm Res. 2021 Mar 5;14:711-718.|[4]ang T, et al. Punicalin Alleviates OGD/R-Triggered Cell Injury via TGF-β-Mediated Oxidative Stress and Cell Cycle in Neuroblastoma Cells SH-SY5Y. Evid Based Complement Alternat Med. 2021 Feb 12;2021:6671282.|[5]Ji W, et al. Punicalin attenuates LPS-induced acute lung injury by inhibiting inflammatory cytokine production and MAPK/NF-κB signaling in mice. Heliyon. 2023 Apr 10;9 (4) :e15434.|[6]Satomi H, et al. Carbonic anhydrase inhibitors from the pericarps of Punica granatum L. Biol Pharm Bull. 1993 Aug;16 (8) :787-90.|[7] Suručić R, et al. Pomegranate peel extract polyphenols attenuate the SARS-CoV-2 S-glycoprotein binding ability to ACE2 Receptor: In silico and in vitro studies. Bioorg Chem. 2021 Sep;114:105145.