IRF6 Antibody
Product Specifications
Background
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.
NCBI Gene ID
3664
Swiss Prot
O14896
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 115-300 of human IRF6 (NP_006138.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Chemokines & Cytokines, Immunology, Innate Immunity, Stem Cell, Transcription
Purification
Affinity purification
Positive Control
22Rv1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 53kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
IRF6
Positive Control 2
BT-474
Positive Control 3
HT-29
Positive Control 4
MCF7
Positive Control 5
293T
Positive Control 6
Mouse liver
NCBI Official Name
Interferon regulatory factor 6
NCBI Organism
Homo sapiens
Other Product Names
IRF6, LPS, OFC6, PIT, PPS, VWS, PPS1, VWS1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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