SERPIND1 Antibody

Product Specifications

Background

This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency.

NCBI Gene ID

3053

Swiss Prot

P05546

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-290 of human SERPIND1 (NP_000176.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 57-69kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

SERPIND1

Positive Control 2

A-431

Positive Control 3

HepG2

Positive Control 4

293T

Positive Control 5

Mouse liver

Positive Control 6

Mouse pancreas

NCBI Official Name

Serpin family D member 1

NCBI Organism

Homo sapiens

Other Product Names

D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH1heparin cofactor 2, leuserpin 2, protease inhibitor leuserpin-2, serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1, serpin D1, serpin peptidase inhibitor, clade D (heparin cofactor), member 1