DCLRE1C Antibody
Product Specifications
Background
This gene encodes a nuclear protein that is involved in V (D) J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
64421
Swiss Prot
Q96SD1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DCLRE1C (NP_001029027.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 45kDa
Fragment
IgG
Symbol
DCLRE1C
Positive Control 2
SW620
Positive Control 3
SW480
Positive Control 4
BT-474
NCBI Official Name
DNA cross-link repair 1C
NCBI Organism
Homo sapiens
Other Product Names
DCLRE1C, A-SCID, DCLREC1C, FLJ11360, FLJ36438, RS-SCID, SCIDA, SNM1C
Tested Applications
WB, IF
Physical Properties
Liquid
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