GRP78 (human, recombinant)

<strong>GRP78 (human, recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2017311_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 74.6 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −80°C_x000D_ <strong>Keywords:</strong> BiP, Glucose-Regulated Protein 78, HspA5_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Thakur G, Sathe G, Kundu I, Biswas B, Gautam P, Alkahtani S, Idicula-Thomas S, Sirdeshmukh R, Kishore U, Madan T. Membrane Interactome of a Recombinant Fragment of Human Surfactant Protein D Reveals GRP78 as a Novel Binding Partner in PC3, a Metastatic Prostate Cancer Cell Line Front Immunol. 2021 Jan 19;11:600660._x000D_ 2: Lam TYW, Nguyen N, Peh HY, Shanmugasundaram M, Chandna R, Tee JH, Ong CB, Hossain MZ, Venugopal S, Zhang T, Xu S, Qiu T, Kong WT, Chakarov S, Srivastava S, Liao W, Kim JS, Teh M, Ginhoux F, Fred Wong WS, Ge R. ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2019161119._x000D_ 3: Wei J, Chen X, Li Y, Li R, Bao K, Liao L, Xie Y, Yang T, Zhu J, Mao F, Ni S, Jia R, Xu X, Li J. Cucurbitacin B-induced G2/M cell cycle arrest of conjunctival melanoma cells mediated by GRP78-FOXM1-KIF20A pathway Acta Pharm Sin B. 2022 Oct;12(10):3861-3876._x000D_ 4: Fabarius A, Samra V, Drews O, Mörz H, Bierbaum M, Darwich A, Weiss C, Brendel S, Kleiner H, Seifarth W, Greffrath W, Hofmann WK, Schmitt CA, Popp HD. Evidence for Recombinant GRP78, CALR, PDIA3 and GPI as Mediators of Genetic Instability in Human CD34+ Cells Cancers (Basel). 2022 Jun 11;14(12):2883._x000D_ 5: Marín-Briggiler CI, González-Echeverría MF, Munuce MJ, Ghersevich S, Caille AM, Hellman U, Corrigall VM, Vazquez-Levin MH. Glucose-regulated protein 78 (Grp78/BiP) is secreted by human oviduct epithelial cells and the recombinant protein modulates sperm-zona pellucida binding Fertil Steril. 2010 Mar 15;93(5):1574-84._x000D_ 6: Tee JH, Vijayakumar U, Shanmugasundaram M, Lam TYW, Liao W, Yang Y, Wong WSF, Ge R. Isthmin-1 attenuates allergic Asthma by stimulating adiponectin expression and alveolar macrophage efferocytosis in mice Respir Res. 2023 Nov 6;24(1):269._x000D_ 7: Ghaderi S, Ahmadian S, Soheili ZS, Ahmadieh H, Samiei S, Kheitan S, Pirmardan ER. AAV delivery of GRP78/BiP promotes adaptation of human RPE cell to ER stress J Cell Biochem. 2018 Feb;119(2):1355-1367._x000D_ 8: Yao VJ, D'Angelo S, Butler KS, Theron C, Smith TL, Marchiò S, Gelovani JG, Sidman RL, Dobroff AS, Brinker CJ, Bradbury ARM, Arap W, Pasqualini R. Ligand-targeted theranostic nanomedicines against cancer J Control Release. 2016 Oct 28;240:267-286._x000D_ 9: Qi AL, Wu Y, Dong N, Chai YF, Zhu XM, Yao YM. Recombinant human ulinastatin improves immune dysfunction of dendritic cells in septic mice by inhibiting endoplasmic reticulum stress-related apoptosis Int Immunopharmacol. 2020 Aug;85:106643._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/26147472">10: Toyoda K, Fukuda T, Sanui T, Tanaka U, Yamamichi K, Atomura R, Maeda H, Tomokiyo A, Taketomi T, Uchiumi T, Nishimura F. Grp78 Is Critical for Amelogenin-Induced Cell Migration in a Multipotent Clonal Human Periodontal Ligament Cell Line J Cell Physiol. 2016 Feb;231(2):414-27. </a>_x000D_ _x000D_ <strong>Products Related to GRP78 (human, recombinant) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>