GLRX Antibody
Product Specifications
Background
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
NCBI Gene ID
2745
Swiss Prot
P35754
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human GLRX (NP_001112362.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
SW480
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 12kDa
Fragment
IgG
Symbol
GLRX
Positive Control 2
NCI-H460
NCBI Official Name
Glutaredoxin (thioltransferase)
NCBI Organism
Homo sapiens
Other Product Names
DRK1, KCB1, KCNB1, Potassium channel Kv2.1, Potassium voltage-gated channel subfamily B member 1
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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